A pair of the nation's stingiest run defenses clash when the Clemson Tigers (2-2) take college football's 13th-ranked run D into a contest with the Syracuse Orange (4-0), who have the No. 21 unit, on Saturday, September 30, 2023. The Tigers are 7-point favorites. The over/under is set at 52.5 in the contest.

You will find odds, spreads, over/unders and more across multiple sportsbooks for the Clemson vs. Syracuse matchup in this article.

Clemson vs. Syracuse Game Info

  • Date: Saturday, September 30, 2023
  • Time: 12:00 PM ET
  • Channel: ABC
  • Live Stream: Watch this game on Fubo
  • City: Syracuse, New York
  • Venue: JMA Wireless Dome

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Clemson vs. Syracuse Odds, Spread, Over/Under

Check out the odds, spread and over/under for this matchup listed at different sportsbooks.

Favorite Total Clemson Moneyline Syracuse Moneyline
BetMGM Clemson (-7) 52.5 -300 +240 Bet on this game with BetMGM
FanDuel Clemson (-7) 53.5 -275 +220 Bet on this game with FanDuel

Week 5 Odds

Clemson vs. Syracuse Betting Trends

  • Clemson has a record of 1-2-0 against the spread this season.
  • The Tigers have covered the spread once when favored by 7 points or more this season (in two opportunities).
  • Syracuse has won two games against the spread this year.

Clemson & Syracuse 2023 Futures Odds

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